DPP-4 Inhibitors
DPP-4 Inhibitors Medications and Options
Browse DPP-4 Inhibitors for type 2 diabetes, compare related tablets and combination options, and find product pages plus safety resources for discussion.
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Every product in this category, in the order patients choose them most. Open a product to see every strength, quantity price and the prescription details.
Prices in USD, the lowest price for each product; your dose and quantity set the final price.
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$39.99 USD cold-packedCold-packed products must ship Express, in medical-grade, temperature-controlled packaging. Dry-packed products ship Express for $29.99. A $50.00 surcharge may apply to cold-packed orders of less than 3 units.
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Compare the most ordered
Active ingredient, comparison prices and starting price for the products patients order most in this category. Your prescriber decides what is right for you.
| Product | Active ingredient | US / Canadian comparison | Starting price (USD) |
|---|---|---|---|
| Januvia | Sitagliptin | US |
From $116.99 You save |
| Tradjenta | Linagliptin | US |
From $85.49 You save |
| Onglyza | Saxagliptin | US |
From $103.49 You save |
| Nesina (Alogliptin) | Alogliptin | US |
From $80.99 You save |
Comparison prices as shown on each product page.
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See tiered pricing →Read the full DPP-4 Inhibitors guide
DPP-4 Inhibitors products in this category are oral diabetes medications for people comparing non-insulin options. This product collection helps patients and caregivers review brand pages, related combination tablets, and condition resources in one place. Use it to compare active ingredients, tablet formats, class fit, and questions to raise with a clinician or prescriber.
Browse DPP-4 Inhibitors products
Dipeptidyl peptidase-4 inhibitors, often called gliptins, are prescription medicines used in type 2 diabetes care. DPP-4 full form refers to dipeptidyl peptidase-4, an enzyme (a protein that helps chemical reactions happen). These medicines work by blocking the DPP-4 enzyme, which may help incretins (gut hormones involved in insulin release after meals) last longer.
The main single-agent product pages in this collection include Januvia, Tradjenta, Nesina, and Onglyza. These DPP-4 inhibitor drugs differ by active ingredient and product labeling, so product pages are more useful than brand-name memory alone.
How to compare tablets, combinations, and related classes
Start by separating single-ingredient medicines from combination tablets. Combination products pair a DPP-4 inhibitor with another diabetes medicine, often metformin. That distinction matters when you already take metformin, have had side effects, or need to avoid duplicate therapy.
Combination pages in this area include Janumet XR and Jentadueto, with related products such as Kazano and Komboglyze also appearing in this class. Review the full active ingredient list before comparing any combination tablet with a single-agent gliptin.
- Check whether the page lists one active ingredient or a combination.
- Match the product form and strength to the prescription label.
- Use the active ingredient, not only the brand name, when comparing options.
- Keep dose questions with the prescriber rather than changing directions yourself.
Quick tip: Combination tablets can duplicate medicine already listed on a current medication list.
Brand names, full form, and common comparison questions
Many users arrive with DPP-4 inhibitors brand names in mind, then need help sorting nearby diabetes categories. Januvia is a DPP-4 inhibitor. Ozempic is not; it belongs to the GLP-1 receptor agonist class. Metformin is also not a DPP-4 inhibitor, although it appears in several diabetes combination tablets.
If you are comparing Jardiance, Farxiga, Ozempic, or metformin with a gliptin, treat those as different categories unless a prescriber has grouped them in your plan. SGLT2 Inhibitors and GLP-1 Agonists can help separate product classes before you open individual medication pages.
| Question | How this category helps |
|---|---|
| Is this a gliptin? | Look for a DPP-4 active ingredient or a listed DPP-4 combination. |
| Is it a single product or combination? | Check whether metformin or another medicine appears in the ingredients. |
| Does it match my prescription? | Compare name, form, strength, and directions with the prescription label. |
Access, cost, and prescription details
DPP-4 Inhibitors cost can vary by product, strength, quantity, pharmacy, and whether cash-pay options apply. This category does not replace a prescription label, benefits review, or clinician guidance. When comparing costs, keep the product name, active ingredient, quantity, and prescriber instructions together.
CanadianInsulin.com functions as a prescription referral platform. Where required, prescription details may be confirmed with your prescriber, and dispensing is handled by licensed third-party pharmacies where permitted.
Safety notes while browsing
Use safety information as a screening tool, not as instructions to start, stop, or change medication. DPP-4 inhibitors side effects and contraindications vary by active ingredient and patient history. Product labels may discuss possible reactions such as headache, upper respiratory symptoms, joint pain, allergic reactions, or pancreas-related warnings. Kidney function, past pancreatitis, allergies, pregnancy, and other medicines may change what a clinician considers appropriate.
No single diabetes pill is safest for every person. Safety depends on diagnosis, kidney and liver function, other medical conditions, current medicines, and treatment goals. Bring an updated medication list to a prescriber or pharmacist when reviewing gliptins side effects, interaction concerns, or possible combination tablets.
Why it matters: A product can look similar online but differ in active ingredient or label directions.
Related condition pages and reading resources
Condition pages and article archives can help you place this product list in context. The Type 2 Diabetes condition page groups diabetes-related products and resources for broader browsing. The Diabetes Articles archive is useful when you want explainers on medication classes, side effects, and common comparisons.
Use related categories when your question is about class differences. Use product pages when your question is about a named medication, strength, or combination ingredient. Use condition resources when you need a wider view of diabetes-related product groups before discussing options with a professional.
Choose your next page with one clear purpose
Before opening a product page, decide what you need to confirm. You may be checking a brand name, comparing a single ingredient with a combination tablet, reviewing safety language, or preparing questions for a prescriber. Clear browsing keeps the category useful without turning it into dosing or treatment advice.
This collection is a starting point for comparing oral non-insulin diabetes medications and related resources. Keep prescription details, active ingredients, and safety questions together as you move between product pages and educational materials.
This content is for informational purposes only and is not a substitute for professional medical advice.
This content is for informational purposes only and is not a substitute for professional medical advice.
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How should I compare products in this category?
Compare products by active ingredient, brand name, tablet form, strength, and whether the page lists a single medicine or a combination. Combination tablets may include metformin or another diabetes medicine, so they should not be treated as the same as single-agent gliptins. Use the prescription label and prescriber instructions as the reference point for any dose or product match.
Is Januvia a DPP-4 inhibitor?
Yes. Januvia is a brand name for sitagliptin, which belongs to the DPP-4 inhibitor class. It appears in this category because users often compare it with other gliptins, such as Tradjenta, Nesina, and Onglyza. Some related combination products may also include sitagliptin with another diabetes medicine, so checking the full ingredient list matters.
Is Ozempic a DPP-4 inhibitor?
No. Ozempic is not a DPP-4 inhibitor. It belongs to the GLP-1 receptor agonist class, which is a different non-insulin diabetes medication group. People often compare these classes because both may be discussed in type 2 diabetes care, but they work differently and have different prescribing considerations.
What is the safest DPP-4 inhibitor?
There is no single safest DPP-4 inhibitor for everyone. Safety depends on your health history, kidney function, allergies, other medications, and the specific product label. A prescriber or pharmacist can help interpret side effects, contraindications, and interactions for an individual medication plan. Product pages can support that discussion, but they should not replace professional review.

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